Isoprene rubber is a synthetic rubber produced using complex catalysts of stereospecific polymerization in solvents. Polyisoprene rubber has the same basic chemical formula as natural rubber (NR). Isoprene rubber is manufactured by the polymerization of synthetic isoprene. Natural rubber is obtained from the milky secretion of different plants. More than 90% of the natural rubber supply comes from Southeast Asia, Becuase rubber trees require a hot, damp climate.